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CCR
T6413 Bindarit Bindarit displays specific inhibition against monocyte chemotactic proteins MCP-1/CCL2, MCP-3/CCL7 and MCP-2/CCL8.
T3430 PF-4136309 INCB8761(PF-4136309) is a specific, effective, and orally bioavailable CCR2 antagonist.
T3188 NSC5844 NSC5844 (RE640) is a bisquinoline compound with C-C chemokine receptor type 1 (CCR1)-agonistic activities.
T2375 BX-471 BX471 is a potent, selective non-peptide CCR1 antagonist.
T6016 Maraviroc Maraviroc is a C-C Chemokine Receptor Type 5 (CCR5) antagonist, and for MIP-1α(IC50=3.3 nM), MIP-1β (IC50=7.2 nM) and RANTES(IC50=5.2 nM).Maraviroc inhibits HIV-1 entry via CCR5 coreceptor interaction.
T4300 AZD2098 AZD2098 is a potent CC-chemokine receptor 4 (CCR4) inhibitor used for asthma research.
T3435 Vicriviroc maleate Vicriviroc maleate(Sch-417690) is a piperazine-based CCR5 receptor antagonist with activity against human immunodeficiency virus. The IC50 value is 0.91 nM in clinical development for the treatment of HIV-1.
T3327 Arteether Arteether is a new, fast-acting antimalarial drug.
T3360 ZK 756326 ZK 756326 is a selective, non-peptide CCR8 chemokine receptor agonist (IC50: 1.8μM, in human; 2.6 μM, in mouse). Displays no activity at CCR4/5 and CXCR3/4 and shows higher 28-fold selectivity over 26 other GPCRs (less selective at α2A and 5-HT receptors). Induces chemotaxis and inhibits Env-m
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