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T0026 Sulfalen Sulfalene, a long-acting sulfonamide antibiotic, is used for the therapy of chronic bronchitis, urinary tract infections, and malaria.
T0087 Sulfacetamide sodium monohydrate Sulfacetamide sodium monohydrate is a sulfonamide antibiotic. It has been investigated for the treatment of rosacea and pityriasis versicolor.
T0087L Sulfacetamide sodium Sulfacetamide Sodium is an anti-infective agent. It is used topically to treat orally for urinary tract infections and skin infections.
T0123 Sulfanilamide Sulfanilamide can competitively inhibit bacterial enzyme dihydropteroate synthetase with IC50 of 320 μM.
T0251 Gemcitabine Gemcitabine is a nucleoside metabolic inhibitor in PANC1(IC50=50 nM), MIAPaCa2(IC50=40 nM), BxPC3(IC50=18 nM) and Capan2 cells(IC50=12 nM).
T0415 Guanidine hydrochloride Guanidine hydrochloride is a strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant.
T0510 Sulfaguanidine Sulfaguanidine, a sulfonamide, is served as an anti-infective agent.
T0618 Indole-3-Glyoxylyl Chloride Indole-3-Glyoxylyl Chloride is an organic compunds with molecular fomula C10H6ClNO2.
T0747 Sulfathiazole Sulfathiazole, an organosulfur compound, has been served as a short-acting sulfa medicine.
T0749 Succinylsulfathiazole Succinylsulfathiazole is a sulfonamide. An ultra long-acting drug.
T0750 Sulfisoxazole Sulfisoxazole is a short-acting sulfonamide antibacterial with activity against a wide range of gram-negative and gram-positive organisms.
T0754 Sulfamethizole Sulfamethizole is a sulfathiazole antibacterial reagent.
T0757 Omeprazole Esomeprazole is the S-isomer of omeprazole, with gastric proton pump inhibitor activity.
T0767 Sulfapyridine Sulfapyridine is a short-acting sulfonamide antibiotic and by-product of the non-steroidal anti-inflammatory drug sulfasalazine.
T0836 Sulfadoxine Sulfadoxine is a broad-spectrum sulfanilamide and a synthetic analog of para-aminobenzoic acid (PABA) with bacteriostatic and antimalarial properties.
T0885 Sulfamethoxazole Sulfamethoxazole is a Sulfonamide Antimicrobial. The mechanism of action of sulfamethoxazole is as a Cytochrome P450 2C9 Inhibitor. The chemical classification of sulfamethoxazole is Sulfonamides.
T0913 Sulfamerazine Sulfamerazine is a long-acting sulfanilamide antibacterial agent. Sulfamerazine inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid (PABA) for the binding site on dihydropteroate synthase.
T0930 Sulfadiazine Sulfadiazine is a synthetic pyrimidinyl sulfonamide derivative, short-acting bacteriostatic Sulfadiazine inhibits bacterial folic acid synthesis by competing with para-aminobenzoic acid. It is used in combination with pyrimethamine to treat toxoplasmosis in patients with acquired immunodeficiency sy
T0987 Gimeracil Gimeracil is a competitive,reversible inhibitor of dihydropyrimidine dehydrogenase.
T1248 Sulfanitran Sulfanitran is a sulfonamide antibiotic used in the poultry industry.
T2128 SBI-0206965 SBI-0206965 is a potent, selective and cell-permeable autophagy kinase ULK1 inhibitor with IC50 of 108 nM for ULK1 kinase activity and 711 nM for ULK2.
T2187 2-Aminobenzenesulfonamide 2-Aminobenzenesulfonamide is a molecule containing the sulfonamide functional group attached to an aniline.
T2188 Thonzonium Bromide Thonzonium bromide is a cationic surface-active compound.
T2731 Usnic Acid Usnic acid is an antimicrobial,antitumor and enzyme inhibiting agent shown to uncouple oxidative phosphorylation in mouse-liver mitochondria. Usnic acid induces necrosis in certain cells.
T2754 Oxymatrine Oxymatrine is an alkaloid isolated from Sophora flavescens, used as the antibiotic. It is a traditional Chinese medicine used in the treatment against hepatitis B virus.
T2888 Pterostilbene Pterostilbene is extracted from Pterocarpus indicus.
T3155 SMER28 SMER28 is a small-molecule enhancer (SMER) of autophagy, inducing autophagy independently of rapamycin in mammalian cells via an mTOR-independent mechanism and prevented the accumulation of amyloid beta peptide.
T3685 SR9009 SR9009, a REV-ERB agonist, increases the constitutive repression of genes regulated by REV-ERBα/ERBβ (IC50: 670/800 nM). Through activation of REV-ERB, SR9009 can decrease circadian locomotor activity during the dark phase and alter the expression pattern of core clock genes in the hypothalami of
T3688 SR9011 SR9011 is a REV-ERB agonist (IC50: 790 nM, REV-ERBα; IC50: 560 nM, REV-ERBβ).
T4123 LYN-1604 <p>LYN-1604 is a novel activator of ULK1, inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.</p>
T4187 Gemcitabine monophosphate Gemcitabine monophosphate disodium salt is a monophosphate derivative of Gemcitabine.
T4219 Autophinib Autophinib is a potent autophagy inhibitor with a novel chemotype with IC50 values of 90 and 40 nM for autophagy in starvation induced autophagy assay and rapamycin induced autophagy assay.
T6056 Thiamet G Thiamet G is a potent, selective O-GlcNAcase inhibitor with Kiof 21 nM, while exhibiting 37,000-fold selectivity over human lysosomal –hexosaminidase.
T6474 Divalproex Sodium Divalproex Sodium binds to and inhibits gamma-aminobutyric acid (GABA) transaminase and its anticonvulsant activity may be exerted by increasing brain concentration of GABA and by inhibiting enzymes that catabolize GABA or block the reuptake of GABA into glia and nerve endings. It also is an HDAC in
T6858 Hydroxyprogesterone caproate Hydroxyprogesterone Caproate is a synthetic progestational agent. It binds to and activates nuclear progesterone receptors in the reproductive system and inhibits ovulation and an alteration in the cervical mucus and endometrium.
T6899 MRT68921 MRT68921 is a potent and dual autophagy kinase ULK1/2 inhibitor with IC50 of 2.9 nM and 1.1 nM, respectively.
T4414 PRIMA-1Met PRIMA-1MET restores wild-type conformation and function to mutant p53, and triggers apoptosis in tumor cells. PRIMA-1MET also targets the selenoprotein thioredoxin reductase 1 (TrxR1), a key regulator of cellular redox balance.
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