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SLAMF2 Protein, Human, Recombinant (hFc & His)

SLAMF2 Protein, Human, Recombinant (hFc & His)

产品编号 TMPJ-00130
别名: Leukocyte antigen MEM-102, CD48 antigen, CD48, BCM1 surface antigen, B-lymphocyte activation marker BLAST-1, BLAST1, TCT.1, BCM1

CD48 antigen, also known as B-lymphocyte activation marker BLAST-1, BCM1 surface antigen, Leukocyte antigen MEM-102, TCT.1, CD48, BCM1,and BLAST1, CD48 contains one Ig-like C2-type domain and one Ig-like V-type domain, but does not have a transmembrane domain, however, but is held at the cell surface by a GPI anchor via a C-terminal domain which maybe cleaved to yield a soluble form of the receptor. CD48 may facilitate interaction between activated lymphocytes and be involved in regulating T-cell activation. CD48 plays a vital role as an environmental sensor for regulating progenitor cell numbers and inhibiting tumor development. It is suggested that the anti-CD48 mAb has the potential to become an effective therapeutic mAb against multiple myeloma.

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SLAMF2 Protein, Human, Recombinant (hFc & His)
规格 价格/CNY 货期 数量
10 μg ¥ 740 5日内发货
50 μg ¥ 1,970 5日内发货
500 μg ¥ 12,100 5日内发货
1 mg ¥ 17,400 5日内发货
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产品目录号及名称: SLAMF2 Protein, Human, Recombinant (hFc & His) (TMPJ-00130)
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产品描述 CD48 antigen, also known as B-lymphocyte activation marker BLAST-1, BCM1 surface antigen, Leukocyte antigen MEM-102, TCT.1, CD48, BCM1,and BLAST1, CD48 contains one Ig-like C2-type domain and one Ig-like V-type domain, but does not have a transmembrane domain, however, but is held at the cell surface by a GPI anchor via a C-terminal domain which maybe cleaved to yield a soluble form of the receptor. CD48 may facilitate interaction between activated lymphocytes and be involved in regulating T-cell activation. CD48 plays a vital role as an environmental sensor for regulating progenitor cell numbers and inhibiting tumor development. It is suggested that the anti-CD48 mAb has the potential to become an effective therapeutic mAb against multiple myeloma.
种属 Human
表达系统 HEK293 Cells
标签 C-hFc-6xHis
蛋白编号 P09326
别名 Leukocyte antigen MEM-102, CD48 antigen, CD48, BCM1 surface antigen, B-lymphocyte activation marker BLAST-1, BLAST1, TCT.1, BCM1
氨基酸序列 Gln27-Ser220
蛋白构建 Gln27-Ser220
蛋白纯度 Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量 71 KDa, reducing conditions
内毒素 < 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液 Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
复溶方法 Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 CD48 antigen, also known as B-lymphocyte activation marker BLAST-1, BCM1 surface antigen, Leukocyte antigen MEM-102, TCT.1, CD48, BCM1,and BLAST1, CD48 contains one Ig-like C2-type domain and one Ig-like V-type domain, but does not have a transmembrane domain, however, but is held at the cell surface by a GPI anchor via a C-terminal domain which maybe cleaved to yield a soluble form of the receptor. CD48 may facilitate interaction between activated lymphocytes and be involved in regulating T-cell activation. CD48 plays a vital role as an environmental sensor for regulating progenitor cell numbers and inhibiting tumor development. It is suggested that the anti-CD48 mAb has the potential to become an effective therapeutic mAb against multiple myeloma.

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Keywords

SLAMF2 Protein, Human, Recombinant (hFc & His) Leukocyte antigen MEM 102 Leukocyte antigen MEM102 Leukocyte antigen MEM-102 BCM 1 CD48 antigen BCM-1 CD 48 CD48 CD-48 BLAST-1 BCM1 surface antigen BLAST 1 B-lymphocyte activation marker BLAST-1 BLAST1 TCT.1 BCM1 recombinant recombinant-proteins proteins protein

 

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