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SARS-CoV-2 NSP8 Protein (His)

SARS-CoV-2 NSP8 Protein (His)

产品编号 TMPJ-01428
别名: SARS-CoV 2 nsp8

Cleavage by the viral main protease, 3CLpro results in generating the nsp8 protein, The nsp8 protein has been shown to associate with several other nsps and to colocalize with these nsps in cytoplasmic complexes that are important for viral RNA synthesis. It forms a hexadecamer with nsp7 (8 subunits of each) that may participate in viral replication by acting as a primase. Alternatively, may synthesize substantially longer products than oligonucleotide primers.Nsp8 was shown to have RNA-dependent RNA polymerase (RdRp) activity that could be involved in producing primers utilized by nsp12 which is normally accepted to be the RdRp for SARS-CoV.

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SARS-CoV-2 NSP8 Protein (His)
规格 价格/CNY 货期 数量
10 μg ¥ 980 5日内发货
50 μg ¥ 2,960 5日内发货
500 μg ¥ 15,800 5日内发货
1 mg ¥ 23,700 5日内发货
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产品目录号及名称: SARS-CoV-2 NSP8 Protein (His) (TMPJ-01428)
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生物活性
技术参数
产品性质
产品描述 Cleavage by the viral main protease, 3CLpro results in generating the nsp8 protein, The nsp8 protein has been shown to associate with several other nsps and to colocalize with these nsps in cytoplasmic complexes that are important for viral RNA synthesis. It forms a hexadecamer with nsp7 (8 subunits of each) that may participate in viral replication by acting as a primase. Alternatively, may synthesize substantially longer products than oligonucleotide primers.Nsp8 was shown to have RNA-dependent RNA polymerase (RdRp) activity that could be involved in producing primers utilized by nsp12 which is normally accepted to be the RdRp for SARS-CoV.
种属 SARS-CoV-2
表达系统 E. coli
标签 C-6xHis
蛋白编号 YP_009725304.1
别名 SARS-CoV 2 nsp8
氨基酸序列 Ala1-Gln198
蛋白构建 Ala1-Gln198
蛋白纯度 Greater than 85% as determined by reducing SDS-PAGE. (QC verified)
分子量 25 KDa (reducing condition)
缓冲液 Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, 10% Glycerol, pH 8.5.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 Cleavage by the viral main protease, 3CLpro results in generating the nsp8 protein, The nsp8 protein has been shown to associate with several other nsps and to colocalize with these nsps in cytoplasmic complexes that are important for viral RNA synthesis. It forms a hexadecamer with nsp7 (8 subunits of each) that may participate in viral replication by acting as a primase. Alternatively, may synthesize substantially longer products than oligonucleotide primers.Nsp8 was shown to have RNA-dependent RNA polymerase (RdRp) activity that could be involved in producing primers utilized by nsp12 which is normally accepted to be the RdRp for SARS-CoV.

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Keywords

SARS-CoV-2 NSP8 Protein (His) SARS-CoV 2 nsp8 recombinant recombinant-proteins proteins protein

 

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