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IL-29 Protein, Human, Recombinant (His)

IL-29 Protein, Human, Recombinant (His)

产品编号 TMPY-01947
别名: IL-29, IFNL1, 白介素, 白细胞介素, interferon, lambda 1, IL29, interferon, λ1

IL-29 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.4 kDa and the accession number is A0A7R8C391.

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IL-29 Protein, Human, Recombinant (His)
规格 价格/CNY 货期 数量
100 μg ¥ 3,930 5日内发货
1 mg ¥ 19,100 5日内发货
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产品目录号及名称: IL-29 Protein, Human, Recombinant (His) (TMPY-01947)
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生物活性
技术参数
产品性质
参考文献
生物活性 Measured in antiviral assays using HepG2 cells infected with vesicular stomatitisvirus (VSV). The ED50 for this effect is typically 4-20 ng/ml.
产品描述 IL-29 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.4 kDa and the accession number is A0A7R8C391.
种属 Human
表达系统 HEK293 Cells
标签 C-His
蛋白编号 A0A7R8C391
别名 IL-29, IFNL1, 白介素, 白细胞介素, interferon, lambda 1, IL29, interferon, λ1
蛋白构建 The Human IL29 (NP_742152.1) (Met 1-Thr 200) was fused with a polyhistidine tag at the C-terminus.
蛋白纯度 > 92 % as determined by SDS-PAGE
分子量 21.4 kDa (predicted)
内毒素 < 1.0 EU/μg of the protein as determined by the LAL method.
缓冲液 Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法 A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice.

研究背景 Interleukin-29 (IL-29), also known as cytokine Zcyto21, Interferon lambda-1, IFN-lambda-1, and IFNL1, is a secreted protein that belongs to the IL-28 / IL-29 family. IL-29 is a cytokine with immunomodulatory activity. IL-29 is highly similar in amino acid sequence to the IL-28. IL-28 and IL-29 are induced by a viral infection and showed antiviral activity. IL-28 and IL-29 interacted with a heterodimeric class II cytokine receptor that consisted of IL-10 receptor beta (IL-10Rbeta) and an orphan class II receptor chain, designated IL-28Ralpha. IL-29 plays an important role in host defenses against microbes and its gene is highly upregulated in cells infected with viruses. IL-29 may play a role in antiviral immunity. IL-29 up-regulates MHC class I antigen expression. It is a Ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway.

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Keywords

IL-29 Protein, Human, Recombinant (His) IFNL-1 IFNL 1 IL 29 IL-29 IFNL1 白介素 白细胞介素 interferon, lambda 1 IL29 interferon, λ1 recombinant recombinant-proteins proteins protein

 

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