GAPDH Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 38 kDa and the accession number is P04406.
生物活性 | Measured by its ability to catalyze D-glyceraldehyde 3-phosphate to 3-phosphoglycerate , the specific activity is >2500pmols/min/ug. |
产品描述 | GAPDH Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 38 kDa and the accession number is P04406. |
种属 | Human |
表达系统 | E. coli |
标签 | N-His |
蛋白编号 | P04406 |
别名 | G3PD, GAPD, HEL-S-162eP, glyceraldehyde-3-phosphate dehydrogenase |
蛋白构建 | The Human GAPDH (P04406) (Met 1-Glu 335) was expressed, with a polyhistidine tag at the N-terminus. |
蛋白纯度 | > 93 % as determined by SDS-PAGE |
分子量 | 38 kDa (predicted) |
内毒素 | Please contact us for more information. |
缓冲液 | Supplied as sterile 50 mM Tris, 30% glycerol, pH 7.5. |
复溶方法 | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
存储 |
It is recommended to store the product under sterile conditions at -20℃ to -80℃. Samples are stable for up to 12 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
运输方式 |
In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
研究背景 | Glyceraldehyde 3-phosphate dehydrogenase (GAPDH or G3PDH) is an enzyme of about 37kDa that is consisdered as a cellular enzyme involved in glycolysis. It catelyzes the sixth step of glycolysis. Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a pleiotropic enzyme that is overexpressed in apoptosis and in several human chronic pathologies. Its role as a mediator for cell death has also been highlighted. A recent report suggests that GAPDH may be genetically associated with late-onset of Alzheimer's disease. Besides, deprenyl, which has originally been used as a monoamine oxidase inhibitor for Parkinson's disease, binds to GAPDH and displays neuroprotective actions. |
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GAPDH Protein, Human, Recombinant (His) G3PD GAPD HEL-S-162eP glyceraldehyde-3-phosphate dehydrogenase recombinant recombinant-proteins proteins protein