Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Sulfadoxine (Sulphadoxine) 是磺胺类化合物,常与pyrimethamine 结合起到抗疟疾作用。它抑制HIV 在外周血单核细胞中的复制。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
500 mg | ¥ 293 | 现货 | ||
1 mL * 10 mM (in DMSO) | ¥ 418 | 现货 |
产品描述 | Sulfadoxine (Sulphadoxine) is a broad-spectrum sulfanilamide and a synthetic analog of para-aminobenzoic acid (PABA) with bacteriostatic and antimalarial properties. |
激酶实验 | Competitive binding assays: Cells are harvested from 150-sq cm T-flasks, and cytosol is prepared at a protein concentration of approximately 2 mg/mL in phosphate buffer. Aliquots of this 180,000 ×g supernatant are then incubated with various concentrations of Tamoxifen and 2.5 nM [3H]estradiol for 16 hr at 0-4 ℃. The free steroids are absorbed by dextran-charcoal [l0 μL of 0.5% Dextran C-5% Norite A in TE buffer] for 1 hr at 0 ℃, and aliquots are counted after centrifugation at 800 ×g, 30 min. The relative binding ability of each competitor is taken as the ratio of the concentration of radioinert estradiol/competitor required to inhibit one-half of the specific [3H]estradiol binding, with the affinity of estradiol set at 100%. |
别名 | 周效磺胺, 磺胺多辛, Sulphadoxine |
分子量 | 310.33 |
分子式 | C12H14N4O4S |
CAS No. | 2447-57-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 57 mg/mL (183.7 mM)
H2O: < 1 mg/mL (insoluble or slightly soluble)
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 3.2224 mL | 16.1119 mL | 32.2238 mL | 80.5594 mL |
5 mM | 0.6445 mL | 3.2224 mL | 6.4448 mL | 16.1119 mL | |
10 mM | 0.3222 mL | 1.6112 mL | 3.2224 mL | 8.0559 mL | |
20 mM | 0.1611 mL | 0.8056 mL | 1.6112 mL | 4.028 mL | |
50 mM | 0.0644 mL | 0.3222 mL | 0.6445 mL | 1.6112 mL | |
100 mM | 0.0322 mL | 0.1611 mL | 0.3222 mL | 0.8056 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Sulfadoxine 2447-57-6 Autophagy Cell Cycle/Checkpoint DNA Damage/DNA Repair Metabolism Microbiology/Virology Proteases/Proteasome DHFR HIV Protease Antibiotic Parasite HIV 周效磺胺 Human immunodeficiency virus 磺胺多辛 inhibit Sulphadoxine Inhibitor inhibitor