Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Levobupivacaine 是一种氨基酰胺类局麻药,属于n-alkylsubstituted pipecoloxylidide 家族。它是bupivacaine 的 S-对映异构体。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
5 mg | ¥ 265 | 现货 | ||
10 mg | ¥ 379 | 现货 | ||
25 mg | ¥ 659 | 现货 | ||
50 mg | ¥ 969 | 现货 | ||
100 mg | ¥ 1,430 | 现货 | ||
200 mg | ¥ 2,130 | 现货 | ||
500 mg | ¥ 3,450 | 现货 | ||
1 mL * 10 mM (in DMSO) | ¥ 231 | 现货 |
产品描述 | Levobupivacaine is an amino-amide local anaesthetic drug belonging to the family of n-alkylsubstituted pipecoloxylidide. It is the S-enantiomer of bupivacaine. Levobupivacaine hydrochloride is commonly marketed by AstraZeneca under the trade name Chirocaine. Compared to bupivacaine, levobupivacaine is associated with less vasodilation and has a longer duration of action. It is approximately 13 per cent less potent (by molarity) than racemic bupivacaine.Levobupivacaine is indicated for local anaesthesia including infiltration, nerve block, ophthalmic, epidural and intrathecal anaesthesia in adults; and infiltration analgesia in children. Adverse drug reactions (ADRs) are rare when it is administered correctly. Most ADRs relate to administration technique (resulting in systemic exposure) or pharmacological effects of anesthesia, however allergic reactions can rarely occur. |
分子量 | 288.43 |
分子式 | C18H28N2O |
CAS No. | 27262-47-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 6 mg/mL (20.8 mM)
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 3.467 mL | 17.3352 mL | 34.6705 mL | 86.6761 mL |
5 mM | 0.6934 mL | 3.467 mL | 6.9341 mL | 17.3352 mL | |
10 mM | 0.3467 mL | 1.7335 mL | 3.467 mL | 8.6676 mL | |
20 mM | 0.1734 mL | 0.8668 mL | 1.7335 mL | 4.3338 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Levobupivacaine 27262-47-1 Membrane transporter/Ion channel Sodium Channel CNS toxicity Inhibitor cardiac toxicity Na+ channels Ferroptosis anaesthetic inhibit analgesic CYP450 NMDA Na channels Erastin gastric cancer inhibitor